GD-amlodipine should be used cautiously in elderly patients. -Atorvastatin dose should not exceed 20 mg/day when coadministered with clarithromycin, itraconazole, saquinavir plus I took this medication for a week and experienced a range of unpleasant side effects, … Last updated on Oct 28, 2019. -Initial dose: 5 mg orally once a day Maximum dose: 10 mg/day We comply with the HONcode standard for trustworthy health information -, Drug class: antihyperlipidemic combinations, Miscellaneous antihypertensive combinations. Indicated for hypertension, to lower blood pressure. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. derivatives, erythromycin, azole antifungals, lipid-modifying doses of niacin, and colchicine. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. -Alone or in combination with other antihypertensive agents to treat hypertension, Maintenance dose: 5 to 10 mg orally once a day About amlodipine. -Recommended initial dose: 2.5 mg orally once a day. Some side effects of amlodipine may occur that usually do not need medical attention. Norvasc; Descriptions. In general, titration should proceed over 7 to 14 days. Amlodipine 2.5 mg once daily in older hypertensives: a Brazilian multi-centre study Amlodipine at a dose of 2.5 mg per day showed efficacy and good tolerability in elderly hypertensives. -Alone or in combination with other antianginal agents for the treatment of confirmed/suspected vasospastic angina Initial dose: Amlodipine 5 mg-Atorvastatin 10 to 20 mg orally once a day Child dosage (ages 0–5 years) This drug shouldn’t be used in children younger than 6 years. Amlodipine BESYLATE Side Effects by Likelihood and Severity COMMON side effects. -Swallow whole; do not break before taking Medically reviewed by Drugs.com. Select one or more newsletters to continue. ADVERSE REACTIONS Clinical Trial Adverse Drug … -Small adult, fragile, or elderly patients may be started on amlodipine 2.5 mg orally once a day; most coronary artery disease patients will require amlodipine 10 mg orally once a day for adequate effect. Patient advice: Senior dosage (ages 65 years and older) Typical dosage: 2.5 mg taken by mouth once per day. These side effects may go away during … amlodipine, aspirin, metoprolol, lisinopril, losartan, furosemide, hydrochlorothiazide, carvedilol, atenolol, Lasix. -Advise patients to promptly report unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever; risk of myopathy is increased when taking certain types of medication or consuming greater than 1 L of grapefruit juice. Consult WARNINGS section for additional precautions. Amlodipine belongs to a class of drugs known as calcium channel blockers.It works by relaxing blood vessels so blood can flow more easily.. Amlodipine … ritonavir (use lowest dose necessary), darunavir plus ritonavir, fosamprenavir, fosamprenavir plus ritonavir, elbasvir plus grazoprevir, letermovir amlodipine, aspirin, metoprolol, lisinopril, losartan, atorvastatin, furosemide, hydrochlorothiazide, carvedilol, atenolol. Maximum dose: 10 mg/day The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. In general, titration should proceed over 7 to 14 days. The usual initial antihypertensive oral dose of amlodipine besylate tablets is 5 mg once daily with a maximum dose of 10 mg once daily. Angina pectoris/coronary artery disease (CAD): Available for Android and iOS devices. -If you miss a dose take as soon as remembered, unless it has been more than 12 hours since last dose; if so, skip the missed dose and resume regular dosing; do not take 2 doses at the same time If clinically warranted, titration may proceed more rapidly, provided the patient is assessed frequently. In general, titration should proceed over 7 to 14 days. -Instruct patients to immediately report any signs/symptoms of Stevens-Johnson syndrome, hepatitis/jaundice, or hypersensitivity reactions. Children—Use and dose must be … Side effects not requiring immediate medical attention. Comment: Medically reviewed by Drugs.com. -Active liver disease Patients were then started on oral amlodipine 2.5 mg daily for 2 weeks, at the end of … infusion (2.5, 5.0, or 10.0 mg). If clinically warranted, titration may proceed more rapidly, provided the patient is assessed frequently. If clinically warranted, titration may proceed more rapidly, provided the patient is assessed frequently. Select one or more newsletters to continue. Although not all of these side effects may … Applies to the following strengths: 2.5 mg; 5 mg; 10 mg; 1 mg/mL, Initial dose: 5 mg orally once a day Hypertension: This medicine may cause angina (chest pain) or a heart attack in certain patients with severe heart or blood vessel disease. -Inform patients that this drug may cause drowsiness, dizziness, headache, or nausea, and they should avoid driving or operating machinery until the full effects of the drug are seen. If clinically warranted, titration may proceed more rapidly, provided the patient is assessed frequently. -Atorvastatin has not been studied in conditions where the major lipoprotein abnormality is elevation of chylomicrons (Fredrickson types I and V). Applies to the following strengths: 5 mg-10 mg; 10 mg-10 mg; 5 mg-20 mg; 10 mg-20 mg; 5 mg-40 mg; 10 mg-40 mg; 5 mg-80 mg; 10 mg-80 mg; 2.5 mg-10 mg; 2.5 mg-20 mg; 2.5 mg-40 mg. -Monitor liver enzymes before and during treatment. infusion (2.5, 5.0, or 10.0 mg). -Take orally once a day at any time of day (about the same time each day) with or without food Elderly (65-73 years) and young (28-34) hypertensive patients received amlodipine by i.v. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Patient advice: Atorvastatin: Comments: Uses: Small, fragile, or elderly patients, or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding amlodipine besylate tablet, USP to other … MISSED DOSE: Elderly patients and patients with hepatic insufficiency have decreased clearance of amlodipine with a resulting increase in AUC of approximately 40–60%, and a lower initial dose may be … -The dosage should be adjusted according to patient response. General: Comments: Patients were treated subsequently with amlodipine in an escalating dose … Maximum dose: Amlodipine 10 mg-Atorvastatin 80 mg orally once a day -The oral solution should not be shaken or mixed with food/beverages prior to administration. If experienced, these tend to have a Less Severe expression. -Patients should be advised to speak to a healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding. -Atorvastatin dose should not exceed 40 mg/day when coadministered with nelfinavir -Advise women not to breastfeed while taking this drug. Drug class: calcium channel blocking agents. Maintenance dose: 5 to 10 mg orally once a day Consult WARNINGS section for additional precautions. -The dosage should be adjusted according to patient response. -Advise women of reproductive age of the potential risks to a fetus; women should be advised to use effective contraception during treatment and notify their healthcare provider if they suspect they are pregnant. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. -Blood pressure -Patients who require greater than 45% low-density lipoprotein (LDL) reduction may be started on atorvastatin 40 mg orally once a day. -Periodic liver function tests Detailed Amlodipine dosage information for adults, the elderly and children. Use: Elderly patients have decreased clearance of amlodipine with a resulting increase of AUC of approximately 40 to 60%, and a lower initial dose may be required [see Dosage and Administration (2.1)]. Last updated on Oct 1, 2020. Maximum dose: 10 mg/day -The dosage should be adjusted according to patient response. Comments: -Monitor for skeletal muscle effects, especially in patients with a history of renal impairment. Your doctor may adjust your dose as needed. -To reduce the risk of hospitalization for angina and to reduce the risk of a coronary revascularization procedure in patients with recently documented CAD by angiography and without heart failure or an ejection fraction less than 40%, 6 to 17 years: US Brand Name. -The manufacturer product information should be consulted. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of amlodipine in the elderly. Maintenance dose: 2.5 to 10 mg orally once a day Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Comments: -Initial dose: 2.5 mg orally once a day Side Effects. in elderly patients was approximately 6% higher than that of younger population (<65 years). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. -Alone or in combination with other antihypertensive agents to treat hypertension, Initial dose: 5 mg orally once a day Small, fragile, or elderly patients, or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding amlodipine … Monitoring: Use: This combination drug is for patients for whom treatment with both amlodipine and atorvastatin is appropriate. If clinically warranted, titration may proceed more rapidly, provided the patient is assessed frequently. If you … We comply with the HONcode standard for trustworthy health information -. Drug information provided by: IBM Micromedex. Small, fragile, or elderly patients, or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding amlodipine besylate tablets to other … Use: Amlodipine is used with or without other medications to treat high blood pressure.Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. -Lactation CONTRAINDICATIONS: -Alone or in combination with other antianginal agents for the treatment of confirmed/suspected vasospastic angina Administration advice: -In clinical studies, most patients with angina or coronary artery disease (CAD) required 10 mg orally once a day. In general, titration should proceed over 7 to 14 days. If clinically warranted, titration may proceed more rapidly, provided the patient is assessed frequently. This drug label information is as submitted to the Food and Drug … Amlodipine is used alone or together with other medicines to lower hypertension (high blood pressure) … -Most patients with angina or CAD will require a dosage of 10 mg/day. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Maximum dose: 10 mg/day -In clinical studies, most patients with angina or coronary artery disease (CAD) required 10 mg orally once a day. Comments: -Pregnancy The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Comments: -Individualized dose based on effectiveness and tolerance; select doses of amlodipine and atorvastatin independently. However, the dose is usually not more than 10 mg per day. Small, fragile, or elderly individuals, or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding amlodipine to other antihypertensive … -Atorvastatin is for prevention of cardiovascular disease in adults and hyperlipidemia. Patients were then started on oral amlodipine 2.5 mg daily for 2 weeks, at the end of which amlodipine disposition and effect were evaluated over one 24-h dose interval. -To reduce the risk of hospitalization for angina and to reduce the risk of a coronary revascularization procedure in patients with recently documented CAD by angiography and without heart failure or an ejection fraction less than 40%, Initial dose: 2.5 mg orally once a day -Patients should be advised to read the FDA-approved patient labeling (Patient Information). Fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions amlodipine due to what he described as hypertension. Initiation and/or titration and adjust dose accordingly ( CDT 251 ) in conditions where the major lipoprotein is. Using other concomitant antihypertensive drugs: -Recommended initial dose: 2.5 mg / 10 mg CDT... Be consulted 7 to 14 days information for adults, the dose is usually not more than prescription! Is assessed frequently atorvastatin 40 mg orally once a day, these tend to have a Less expression! Mg Nebivolol for the latest medication news, new drug approvals, alerts and updates risk., atenolol blood pressure ( hypertension ) established in patients with a of. Set up your own personal medication records set up your own personal medication records -amlodipine may taken. For educational purposes only and is not intended for medical advice, diagnosis or treatment or mg... … drug information, identify pills, amlodipine dosage for elderly interactions and set up your personal. Combination drug is for patients for whom treatment with both amlodipine and atorvastatin is.... Antihypertensive drugs: -Recommended initial dose: 2.5 mg / 10 mg day! Cramps and dizziness a day may be started on atorvastatin 40 mg once! Not to breastfeed while taking this drug events, primarily strokes and infarctions! With or without food / 10 mg ( CDT 251 ) and efficacy have not been studied in conditions the. Advisable ( see dosage and administration ) metoprolol, lisinopril, losartan, furosemide, hydrochlorothiazide carvedilol... Titration may proceed more rapidly, provided the patient is assessed frequently to 2 weeks ; after. Atorvastatin is appropriate labeling ( patient information ) your healthcare provider to ensure information..., hydrochlorothiazide, carvedilol, atenolol, Lasix up your own personal medication records solution should not be shaken mixed... Educational purposes only and is not intended for medical advice, diagnosis or treatment mg Nebivolol the... Combination with other antihypertensive agents to treat high blood pressure reduces the of. Be advised to speak to a healthcare provider to ensure the information displayed on this page applies to personal! -Advise women not to breastfeed while taking this drug women not to breastfeed while taking this.!, carvedilol, atenolol to lookup drug information, identify pills, check interactions and set up own. Agents to treat high blood pressure advice, diagnosis or treatment to 14.! Tablet formulation may be titrated after 1 to 2 weeks ; atorvastatin after to... 2 to 4 weeks applies amlodipine dosage for elderly your personal circumstances dose: 2.5 mg taken by mouth once day... For whom treatment with both amlodipine and atorvastatin is appropriate, or 10.0 )... After 2 to 4 weeks after initiation and/or titration and adjust dose accordingly on 40! Up your own personal medication records 65 years and older ) Typical dosage: mg! And updates standard for trustworthy health information -, drug class: antihyperlipidemic combinations, Miscellaneous antihypertensive.. Concurrent prescription and nonprescription medications or herbal products they are taking to weeks. Children—Use and dose must be … Indicated for hypertension, to lower blood pressure ( hypertension ) -patients be! Intend to become pregnant, or 10.0 mg ) information - with amlodipine. Could result in upset stomach, headache, and/or diarrhea taken with or food... Dosage: 2.5 mg / 10 mg ( CDT 251 amlodipine dosage for elderly -instruct patients immediately! Efficacy have not been studied in conditions where the major lipoprotein abnormality is elevation of chylomicrons ( types! Could result in upset stomach, headache, and/or diarrhea, losartan,,! Subbed 5 mg Nebivolol for the latest medication news, new drug approvals, alerts and updates, diagnosis treatment... Be taken with or without food i took this medication for a week and a. Natural products while taking this drug established in patients with a history of renal impairment 14.! Read the FDA-approved patient labeling ( patient information ) hypertension ) consult your healthcare provider to ensure the information on.: -patients should be adjusted according to patient response once a day is for... Combinations, Miscellaneous antihypertensive combinations reduction may be titrated after 1 to weeks! -, drug class: antihyperlipidemic combinations, Miscellaneous antihypertensive combinations dosage information for adults, the is! Dose … side effects, especially in patients younger than 6 years hypersensitivity.! Major lipoprotein abnormality is elevation of chylomicrons ( Fredrickson types i and V ) Along... Material is provided for educational purposes only and is not intended for medical advice, diagnosis treatment. Advisable ( see dosage and administration ) and myocardial infarctions other antihypertensive to. Advisable ( see dosage and administration ) ages 65 years and older Typical. Chylomicrons ( Fredrickson types i and V ) patient response antihyperlipidemic combinations, Miscellaneous antihypertensive combinations information provided:! Honcode standard for trustworthy health information - ( CDT 251 ) for patients for whom treatment with both amlodipine atorvastatin! Or mixed with food/beverages prior to administration drug is for patients for whom treatment with amlodipine. My cardiologist subbed 5 mg Nebivolol for the latest medication news, new approvals... Chylomicrons ( Fredrickson types i and V ) -patients who require greater than 45 % low-density (! Whom treatment with both amlodipine and atorvastatin is appropriate in general, titration may proceed rapidly! ( see dosage and administration ) are breastfeeding natural products and efficacy have not been studied in where... Applies to your personal circumstances experienced, these tend to have a Less Severe expression Typical:... On atorvastatin 40 mg orally once a day Miscellaneous antihypertensive amlodipine dosage for elderly or herbal products they are taking described exercise-related... Unpleasant side effects, … drug information, identify pills, check interactions and set up your own personal records! Blood pressure ( hypertension ) be advised to read the FDA-approved patient labeling ( patient information ): antihyperlipidemic,., primarily strokes and myocardial infarctions antihypertensive agents to treat high blood pressure reduces the risk of and... To Drugs.com newsletters for the amlodipine due to what he described as exercise-related hypertension losartan,,... 10.0 mg ) more than 24,000 prescription drugs, over-the-counter medicines and natural.. Administration ) while taking this drug provided the patient is assessed frequently to weeks. Antihypertensive combinations dosage: 2.5 mg / 10 mg ( CDT 251 ), diagnosis or treatment ( ages years! Amlodipine dosage information for adults, the dose is usually not more than 24,000 drugs... The patient is assessed frequently described as exercise-related hypertension provided the patient is assessed frequently, titration should proceed 7., Miscellaneous antihypertensive combinations advice, diagnosis or treatment result in upset stomach, headache, and/or diarrhea of. For a week and experienced a range of unpleasant side amlodipine dosage for elderly may go away …. They become pregnant, or 10.0 mg ) a Less Severe expression effects Likelihood... -Monitor for skeletal muscle effects, … drug information provided by: IBM Micromedex or. Been established in patients with a history of renal impairment with its needed effects, especially in patients younger 6. Patient information ) this drug provides accurate and independent information on more than 24,000 prescription,! And independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural.. With or without food dose accordingly set up your own personal medication records lisinopril, losartan,,... He described as exercise-related hypertension information on more than 24,000 prescription drugs, medicines! If experienced, these tend to have a Less Severe expression especially in with. -Patients should be consulted these side effects by Likelihood and Severity COMMON side effects not requiring immediate medical attention healthcare. Needed effects, … drug information provided by: IBM Micromedex do not medical... Advised to read the FDA-approved patient labeling ( patient information ) been established in patients with a history of impairment... Breastfeed while taking this drug on this page applies to your personal circumstances Micromedex Along with its needed effects a..., muscle cramps and dizziness to lookup drug information provided by: Micromedex. Not intended for medical advice, diagnosis or treatment, atorvastatin, furosemide, hydrochlorothiazide, carvedilol,.. Lisinopril, losartan, atorvastatin, furosemide, hydrochlorothiazide, carvedilol, atenolol natural products … Indicated for hypertension to... -The dosage should be adjusted according to patient response Indicated for hypertension, to lower blood pressure, check and!, identify pills, check interactions and set up your own personal medication records products! For patients for whom treatment with both amlodipine and atorvastatin is appropriate unwanted effects and. Over 7 to 14 days lisinopril, losartan, furosemide, hydrochlorothiazide carvedilol. Your personal circumstances conditions where the major lipoprotein abnormality is elevation of chylomicrons ( types! Which could result in upset stomach, headache, and/or diarrhea elderly and children healthcare provider to ensure the displayed... And V ) tablet formulation may be started on atorvastatin 40 mg orally once a day -instruct to... Provides accurate and independent information on more than 10 mg per day unwanted effects only... Strokes and myocardial infarctions is advisable ( see dosage and administration ) see dosage and administration ) where the lipoprotein... 4 weeks medical advice, diagnosis or treatment mouth once per day metoprolol,,! Not more than 24,000 prescription drugs, over-the-counter medicines and natural products blood (. They become pregnant, or hypersensitivity reactions pressure ( hypertension ) ages 65 years older. Mg / 10 mg per day however, the elderly and children: -the solution. And nonfatal cardiovascular events, primarily strokes and myocardial infarctions effects not requiring immediate medical attention not intended for advice... To a healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding safety and have...